A method for MR imaging of prostate cancer patients in the radiotherapy treatment position without loss of image quality

نویسندگان

  • S. Hanvey
  • J. Foster
  • M. Glegg
چکیده

Introduction: Modern radiotherapy treatment planning (RTTP) requires volumetric localisation of tumour and critical structures. 3dimensional computed tomography (CT) data is the preferred imaging modality in RTTP due to: spatial accuracy; electron density information; the speed of acquisition; the ability to image the patient in the treatment position and the visualisation of bony anatomy. However, magnetic resonance imaging (MRI) provides superior soft tissue contrast over CT and it has been shown that improved prostate and rectal volume delineation from MRI has the potential to improve target coverage and rectal sparing [1]. It is therefore desirable to integrate MR data into the treatment planning process. MR suffers from geometric distortion and gives no electron density information and so most hospitals rely on the CT scans to plan treatment. CT-MR fusion introduces errors as a result of changes in patient positioning from diagnostic and planning scans, potentially giving inaccuracies in the delineation of the target volume. Patient positioning problems can be overcome by taking the MR diagnostic scans in the same position as the radiotherapy treatment. For pelvic tumour patients a flat table is required since image registration with a curved table introduces fusion inaccuracies, as shown in figure 1. Patients are not routinely scanned on a flat table in MR because clinicians do not wish to compromise diagnostic information for positional accuracy. This study investigates a method for maintaining satisfactory diagnostic information in MR while positioning the patient in the CT and radiotherapy treatment positions using a customised flat table, patient immobilisation, a laser positioning system and a suitable imaging coil.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID)

Background: To correct patient positioning errors (setup errors) during prostate cancer treatment using EPID and fiducial gold markers, to improve the accuracy of the dose delivery in these patients. Materials and Methods: Fifteen patients with localized prostate carcinoma after implantation of fiducial gold markers in their prostate gland underwent the five-field IMRT planning technique. The p...

متن کامل

Integrating fMRI data into 3D conventional radiotherapy treatmentplanning of brain tumors

Introduction: This study was aimed to investigate the beneficial effects of functional magnetic resonance imaging (fMRI) data in treatment planning for patients with CNS tumors in order to decrease the injury of functional regions of the brain followed by increase in life quality and survival of patients. This study pursues a novel approach in planning for the treatment of brai...

متن کامل

Early toxicity of moderate hypofractionated volumetric modulated Arc radiotherapy for localized prostate cancer

Background: Based on the radiation biology model of prostate cancer, hypofractionated radiotherapy can improve the treatment outcomes without increasing toxicity. Although hypofractionated radiotherapy is implemented over a short period of time, it is more convenient and cheaper compared with conventional fractionated treatment. The aim of this study was to investigate the early toxicity of mod...

متن کامل

Optimization of clinical target volume delineation using magnetic resonance spectroscopic imaging (MRSI) in 3D conformal radiotherapy of prostate cancer

Background: For the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, MRSI was used as a molecular imaging modality with MRI and CT images. Materials and Methods: The images of 20 prostate cancer patients were used in this study. The MR and MRSI images were registered with CT ones using non-rigid registration technique. The CT based planning (BP), CT/MR...

متن کامل

Image-guided prostate radiotherapy: analysis of inter- fractional setup errors

Introduction: The accuracy of the patient setup and tumor location are major factors that determine the efficacy of radiotherapy treatment planning. In the prostate radiotherapy, reproducibility of the prostate location for each treatment fraction is problematic owing to varying filling of the rectum and bladder. According to this, the aim of this study was to measure the inte...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008